EB2 pS222 antibody
Por um escritor misterioso
Descrição
EB2 S222 site is a target for phosphorylation by the CDKL5 protein kinase; loss-of-function mutations in the human CDKL5 gene are associated with CDKL5 Deficiency Disorder, a neurodevelopmental disorder with intractable epilepsy (Baltussen, Negraes, et al
PDF) Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125
Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125, Microbial Cell Factories
Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125, Microbial Cell Factories
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective
Litterature
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. - Abstract - Europe PMC
Litterature
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics
Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125, Microbial Cell Factories
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
JCI - Temporal manipulation of Cdkl5 reveals essential postdevelopmental functions and reversible CDKL5 deficiency disorder–related deficits
Litterature
Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
PDF) A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
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